Self-isolation guidance is to end this weekend for people in Scotland who have Covid-19 or symptoms of the virus.
From Sunday, public health advice will change to a "stay at home" message for people who feel unwell or have a fever.
They will no longer be advised to take a PCR test and all contact tracing will end.
The changes, part of the Test and Protect Transition Plan which was published last month, will also see all contact tracing ending.
Testing for the general population will end tomorrow with test sites closing at that point too. However, testing will remain available to certain groups in order to protect high risk settings, support clinical care and for surveillance purposes.
Those groups include health and social care workers, care home and hospital visitors, patients groups eligible for treatment, hospital patients, unpaid carers and people in prison.
Other adults who have symptoms of Covid-19 and other respiratory illnesses and have a high temperature or do not feel well enough to go to work or carry out normal activities, are advised to stay at home until their fever has gone or they feel well enough.
The Protect Scotland app will also be closed down shortly, but users are encouraged to keep the app on their phones in case it is needed again at a future date.
NHS Scotland will also be taken out of emergency footing at the end of Saturday 30 April as Covid-19 cases continue to fall.
Health Secretary Humza Yousaf said: “Scotland’s Test and Protect programme has been one of the key interventions in our response to Covid-19, the success of which has been due, in no small part, to the remarkable staff and volunteers working in Test and Protect - my sincere thanks go to them.
“I would also like to thank the Scottish public for their commitment and willingness to engage with Test and Protect when it was required of them and helping to protect their fellow citizens.
“However, we recognise we are now in a different phase of the pandemic. The primary purpose of testing is changing from population-wide testing to reduce transmission, to a targeted response focused on reducing severe harm of the virus.
“As we are now seeing a steady reduction in new Covid cases, the NHS will no longer remain on emergency footing after Saturday 30 April. But we must continue with a measured approach to support the recovery and renewal of our NHS.
“This will require balancing capacity of the NHS and the wellbeing of the workforce to respond to increasing demands for urgent care while reducing the backlog of planned care.”