Sir Keir Starmer says a landmark agreement between the UK and US is set to usher in a "golden age" for nuclear energy.
The two nations are expected to officially complete the deal this week during Donald Trump's state visit.
But while the Atlantic Partnership for Advanced Nuclear Energy is expected to create thousands of jobs, Scotland could miss out due to the SNP's dislike of nuclear, The Telegraph reports.
Scotland's job growth in the sector was the lowest in the UK over the past year, according to the Nuclear Industry Association.
While energy policy is controlled by Westminster, the SNP has utilised devolved planning powers to block nuclear projects north of the border.
Scotland's only remaining nuclear power facility, Torness, is scheduled to close in 2030.
The Telegraph quotes NIA chief executive Tom Greatrex as saying: "Scotland will miss out on thousands of new jobs and economic growth while England is seeing billions invested in nuclear projects that have the scale to transform local communities.
"If the Scottish government continues with a misguided policy, ignorant of evidence and rooted in prejudice, then communities in Scotland will see new jobs, new investment and new opportunities in the green economy pass them by."
The UK-US deal is designed to fast-track regulatory and licensing processes to speed up construction of new nuclear power stations here and in America.
It is hoped, the BBC reports, that the deal will unlock billions in private investment, as well as boost commercial partnerships between British and American firms.