The Confederation of British Industry (CBI) has warned action is needed to halt the exodus of companies from the London Stock Exchange.
CBI said 213 firms have chosen to leave since 2016, citing a combination of firms choosing to list elsewhere, private companies buying public ones, and investors shunning UK shares.
The BBC reports Rupert Soames, chairman of the leading business group, said the sector is now at a "pivotal moment" in the UK.
To turn the tide, he called for lighter regulation, improved marketing and incentives for investors in British firms.
He is also supportive of cutting tax breaks for those putting savings in cash ISAs in a bid to encourage more investment in stocks and shares, something Rachel Reeves is thought to be considering.
"Of all the investments that God ever invented, cash [ISA] is the worst possible one," he said.