Shell is axing around 200 jobs from its low-carbon division next year in an effort to "simplify its business structure".
A further 130 jobs are under review, although a Shell spokesperson said some of the affected employees will be will be integrated into other parts of the company.
The company has yet to comment on the locations of the roles affected.
Staff were told of the job cuts in an internal memo, although they won't be happening until next year.
The cuts come as new chief executive Wael Sawan seeks to improve returns to investors by refocusing on the group's oil and gas projects.
Refocusing the hydrogen business
"We are transforming our Low Carbon Solutions (LCS) business to strengthen its delivery on our core low-carbon business areas such as transport and industry," the company said.
Shell's low-carbon team does not include staff working within the company's renewable power business.
The scale back impacts primarily on Shell's hydrogen light mobility operations, which develop technologies for light passenger vehicles, and will focus on heavy mobility and industry.
The company was one of the first backers of hydrogen-fuelled cars, although has been forced to close a number of hydrogen fuelling station across the country in recent years as consumers opt for electric vehicles.
"Our global hydrogen portfolio remains a key part of our efforts to address the commercial and technical challenges in scaling our Low Carbon Solutions business," Shell said.
"We will be disciplined in only making investments with the highest chance of creating value and lowering emissions."